A Mini-Review 5-Amino-N-Substituted Pyrazoles as Building Blocks for Bioactive Molecules

Bawazir, Wafa (2020) A Mini-Review 5-Amino-N-Substituted Pyrazoles as Building Blocks for Bioactive Molecules. International Journal of Organic Chemistry, 10 (02). pp. 63-76. ISSN 2161-4687

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Abstract

In this review a five-membered heterocyclic ring having two adjacent nitrogen atoms known as Pyrazole, we have framed 5-amino-N-substituted pyrazoles in particular focusing on its substantial role as a building block and starting materials for producing enormous heterocyclic skeletons. The existence of this moiety in larger compounds renders them to expose medicinal, pharmacological and biological therapeutic activities. Enormous drugs contain 5-amino-N-substituted pyrazoles such as celecoxib anti-inflammatory, antipsychotic, anti-obesity, analgesic, and antidepressant. We reported various routes of synthesis and the use of these compounds.

Item Type: Article
Subjects: Scholar Eprints > Chemical Science
Depositing User: Managing Editor
Date Deposited: 01 Mar 2023 05:17
Last Modified: 24 Sep 2024 12:18
URI: http://repository.stmscientificarchives.com/id/eprint/655

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